BDBM50005285 CHEMBL3114531

SMILES: OCC1(CNC(=O)c2nc3c(cccc3n2CC(F)(F)F)-c2ccccc2)CCCCC1

InChI Key: InChIKey=WSLLFUZFPYVTFT-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50005285   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50005285 (CHEMBL3114531) Show SMILES OCC1(CNC(=O)c2nc3c(cccc3n2CC(F)(F)F)-c2ccccc2)CCCCC1 Show InChI InChI=1S/C24H26F3N3O2/c25-24(26,27)15-30-19-11-7-10-18(17-8-3-1-4-9-17)20(19)29-21(30)22(32)28-14-23(16-31)12-5-2-6-13-23/h1,3-4,7-11,31H,2,5-6,12-16H2,(H,28,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.70E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation after 1 hr				Bioorg Med Chem Lett 24: 1218-21 (2014) Article DOI: 10.1016/j.bmcl.2013.12.068 BindingDB Entry DOI: 10.7270/Q2FJ2J9K
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50005285 (CHEMBL3114531) Show SMILES OCC1(CNC(=O)c2nc3c(cccc3n2CC(F)(F)F)-c2ccccc2)CCCCC1 Show InChI InChI=1S/C24H26F3N3O2/c25-24(26,27)15-30-19-11-7-10-18(17-8-3-1-4-9-17)20(19)29-21(30)22(32)28-14-23(16-31)12-5-2-6-13-23/h1,3-4,7-11,31H,2,5-6,12-16H2,(H,28,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.97E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation after 1 hr				Bioorg Med Chem Lett 24: 1218-21 (2014) Article DOI: 10.1016/j.bmcl.2013.12.068 BindingDB Entry DOI: 10.7270/Q2FJ2J9K
					More data for this Ligand-Target Pair