null

SMILES: CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)NCc1cc(Cl)ccc1Cl

InChI Key: InChIKey=ZTUTWOVXSWGGSQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50005490   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50005490 (CHEMBL138702 | CHEMBL3234263) Show SMILES CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)NCc1cc(Cl)ccc1Cl Show InChI InChI=1S/C20H16Cl2N2O3S/c1-2-24-17-8-9-18(14-4-3-5-15(19(14)17)20(24)25)28(26,27)23-11-12-10-13(21)6-7-16(12)22/h3-10,23H,2,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at Gal4-fused RORgamma (unknown origin) expressed in 293T cells after 24 hrs by luciferase reporter gene assay				Eur J Med Chem 78: 431-41 (2014) Article DOI: 10.1016/j.ejmech.2014.03.065 BindingDB Entry DOI: 10.7270/Q2W66N9X
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50005490 (CHEMBL138702 | CHEMBL3234263) Show SMILES CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)NCc1cc(Cl)ccc1Cl Show InChI InChI=1S/C20H16Cl2N2O3S/c1-2-24-17-8-9-18(14-4-3-5-15(19(14)17)20(24)25)28(26,27)23-11-12-10-13(21)6-7-16(12)22/h3-10,23H,2,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at human His6-tagged RORgamma ligand binding domain (262 to 507 aa) assessed as inhibition of SRC1-4 co-activator peptide recruit...				Eur J Med Chem 78: 431-41 (2014) Article DOI: 10.1016/j.ejmech.2014.03.065 BindingDB Entry DOI: 10.7270/Q2W66N9X
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50005490 (CHEMBL138702 | CHEMBL3234263) Show SMILES CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)NCc1cc(Cl)ccc1Cl Show InChI InChI=1S/C20H16Cl2N2O3S/c1-2-24-17-8-9-18(14-4-3-5-15(19(14)17)20(24)25)28(26,27)23-11-12-10-13(21)6-7-16(12)22/h3-10,23H,2,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at full-length RORgamma (unknown origin) expressed in 293T cells after 24 hrs by luciferase reporter gene assay				Eur J Med Chem 78: 431-41 (2014) Article DOI: 10.1016/j.ejmech.2014.03.065 BindingDB Entry DOI: 10.7270/Q2W66N9X
					More data for this Ligand-Target Pair