BDBM50005683 2-Cyclohexyl-2-phenyl-propionic acid 4-diethylamino-butyl ester::CHEMBL285898
SMILES: CCN(CC)CCCCOC(=O)C(C)(C1CCCCC1)c1ccccc1
InChI Key: InChIKey=HXBKNTPSKWVIGR-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50005683 (2-Cyclohexyl-2-phenyl-propionic acid 4-diethylamin...) | UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 111 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Research Curated by ChEMBL | Assay Description Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine... | J Med Chem 35: 1290-5 (1992) BindingDB Entry DOI: 10.7270/Q28914T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50005683 (2-Cyclohexyl-2-phenyl-propionic acid 4-diethylamin...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Research Curated by ChEMBL | Assay Description Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine... | J Med Chem 35: 1290-5 (1992) BindingDB Entry DOI: 10.7270/Q28914T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human)) | BDBM50005683 (2-Cyclohexyl-2-phenyl-propionic acid 4-diethylamin...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 209 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Research Curated by ChEMBL | Assay Description Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine... | J Med Chem 35: 1290-5 (1992) BindingDB Entry DOI: 10.7270/Q28914T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50005683 (2-Cyclohexyl-2-phenyl-propionic acid 4-diethylamin...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 248 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Research Curated by ChEMBL | Assay Description Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine... | J Med Chem 35: 1290-5 (1992) BindingDB Entry DOI: 10.7270/Q28914T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Rattus norvegicus) | BDBM50005683 (2-Cyclohexyl-2-phenyl-propionic acid 4-diethylamin...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Research Curated by ChEMBL | Assay Description Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells. | J Med Chem 35: 1290-5 (1992) BindingDB Entry DOI: 10.7270/Q28914T0 | |||||||||||
More data for this Ligand-Target Pair |