BDBM50006275 6-Carboxymethyl-12-(3-guanidino-propyl)-15-(1H-indol-3-ylmethyl)-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentaaza-cyclooctadecane-3-carboxylic acid::CHEMBL60388

SMILES: NC(=N)NCCC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)CNC1=O)C(O)=O

InChI Key: InChIKey=PIVQYHTZYSKTOM-MUGJNUQGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50006275   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50006275 (6-Carboxymethyl-12-(3-guanidino-propyl)-15-(1H-ind...) Show SMILES NC(=N)NCCC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)CNC1=O)C(O)=O Show InChI InChI=1S/C28H37N9O9S/c29-28(30)31-7-3-6-17-24(42)33-11-21(38)34-19(9-23(40)41)26(44)37-20(27(45)46)12-47-13-22(39)35-18(25(43)36-17)8-14-10-32-16-5-2-1-4-15(14)16/h1-2,4-5,10,17-20,32H,3,6-9,11-13H2,(H,33,42)(H,34,38)(H,35,39)(H,36,43)(H,37,44)(H,40,41)(H,45,46)(H4,29,30,31)/t17-,18-,19-,20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 35: 2040-8 (1992) BindingDB Entry DOI: 10.7270/Q2S1833Q
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50006275 (6-Carboxymethyl-12-(3-guanidino-propyl)-15-(1H-ind...) Show SMILES NC(=N)NCCC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)CNC1=O)C(O)=O Show InChI InChI=1S/C28H37N9O9S/c29-28(30)31-7-3-6-17-24(42)33-11-21(38)34-19(9-23(40)41)26(44)37-20(27(45)46)12-47-13-22(39)35-18(25(43)36-17)8-14-10-32-16-5-2-1-4-15(14)16/h1-2,4-5,10,17-20,32H,3,6-9,11-13H2,(H,33,42)(H,34,38)(H,35,39)(H,36,43)(H,37,44)(H,40,41)(H,45,46)(H4,29,30,31)/t17-,18-,19-,20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 35: 2040-8 (1992) BindingDB Entry DOI: 10.7270/Q2S1833Q
					More data for this Ligand-Target Pair