BDBM50006897 CHEMBL3237241

SMILES: Cc1c(Cc2ccc(=O)n(Cc3cccc(F)c3)n2)c2cc(F)ccc2n1CC(O)=O

InChI Key: InChIKey=FUFRURSHUGZLGV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006897   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50006897 (CHEMBL3237241) Show SMILES Cc1c(Cc2ccc(=O)n(Cc3cccc(F)c3)n2)c2cc(F)ccc2n1CC(O)=O Show InChI InChI=1S/C23H19F2N3O3/c1-14-19(20-10-17(25)5-7-21(20)27(14)13-23(30)31)11-18-6-8-22(29)28(26-18)12-15-3-2-4-16(24)9-15/h2-10H,11-13H2,1H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CRTh2 expressed in CHO-K1 cells by cAMP TR FRET assay				J Med Chem 57: 1299-322 (2014) Article DOI: 10.1021/jm401509e BindingDB Entry DOI: 10.7270/Q21V5GGH
					More data for this Ligand-Target Pair