BDBM50006914 (2-Butyl-5-chloro-3-{4-[2-(2H-tetrazol-5-yl)-cyclohex-1-enyl]-benzyl}-3H-imidazol-4-yl)-methanol::CHEMBL314149

SMILES: CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)C1=C(CCCC1)c1nnn[nH]1

InChI Key: InChIKey=HNGCRAXRWVPURO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006914   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT1B (RAT)	BDBM50006914 ((2-Butyl-5-chloro-3-{4-[2-(2H-tetrazol-5-yl)-cyclo...) Show SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)C1=C(CCCC1)c1nnn[nH]1 |t:21| Show InChI InChI=1S/C22H27ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h9-12,30H,2-8,13-14H2,1H3,(H,25,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Concentration of the compound required to inhibit binding of radioligand [125I]-AII to angiotensin II receptor, type 1 in rat adrenal glomerulosa tis...				J Med Chem 35: 2658-67 (1992) BindingDB Entry DOI: 10.7270/Q2930S4R
					More data for this Ligand-Target Pair