null
SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)C(C)(C)NC(=O)C(C)(C)NC(=O)[C@H](Cc1ccc(O)cc1)N(CC=C)CC=C)C(O)=O
InChI Key: InChIKey=XUWLAGNFLUARAN-CHQNGUEUSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding affinity towards opioid receptor delta 1 expressed in CHO cells was determined by using [3H]DPDPE as radioligand | J Med Chem 47: 281-4 (2004) Article DOI: 10.1021/jm030419a BindingDB Entry DOI: 10.7270/Q20K2990 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of opioid receptor kappa | J Med Chem 33: 1714-20 (1990) BindingDB Entry DOI: 10.7270/Q27P9003 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description The compound was evaluated for binding affinity against Opioid receptor delta 1 in guinea pig brain membrane using [3H]- DPDPE as ligand | J Med Chem 35: 4325-9 (1992) BindingDB Entry DOI: 10.7270/Q2DF6RTZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity at Opioid receptor delta 1 in guinea pig brain membranes | J Med Chem 34: 1757-62 (1991) BindingDB Entry DOI: 10.7270/Q2DZ08XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Binding affinity was measured by the displacement of [3H]- DADLE in guinea pig brain membrane of opioid receptor delta | J Med Chem 33: 1714-20 (1990) BindingDB Entry DOI: 10.7270/Q27P9003 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description The compound was evaluated for binding affinity against opioid receptor mu in guinea pig brain membranes using [3H]- DAMGO as ligand | J Med Chem 35: 4325-9 (1992) BindingDB Entry DOI: 10.7270/Q2DF6RTZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of Opioid receptor kappa 1 | J Med Chem 33: 1714-20 (1990) BindingDB Entry DOI: 10.7270/Q27P9003 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Binding affinity was measured by the displacement of [3H]- DAMGO in guinea pig brain membrane of opioid receptor mu | J Med Chem 33: 1714-20 (1990) BindingDB Entry DOI: 10.7270/Q27P9003 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description The compound was evaluated for binding affinity against the opioid receptor kappa in guinea pig brain membranes using [3H]- U-69,593 | J Med Chem 35: 4325-9 (1992) BindingDB Entry DOI: 10.7270/Q2DF6RTZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity of Opioid receptor kappa 1 in guinea pig brain membranes | J Med Chem 34: 1757-62 (1991) BindingDB Entry DOI: 10.7270/Q2DZ08XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity at Opioid receptor mu 1 in guinea pig brain membranes | J Med Chem 34: 1757-62 (1991) BindingDB Entry DOI: 10.7270/Q2DZ08XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Binding affinity was measured by the displacement of [3H]- DAMGO in guinea pig brain membrane of Opioid receptor mu 1 | J Med Chem 33: 1714-20 (1990) BindingDB Entry DOI: 10.7270/Q27P9003 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of Opioid receptor kappa 1 | J Med Chem 33: 1714-20 (1990) BindingDB Entry DOI: 10.7270/Q27P9003 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.89E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Binding affinity was measured in cloned Opioid receptor mu 1 expressed in CHO cells using [3H]- DAMGO as radioligand. | J Med Chem 43: 3941-8 (2000) BindingDB Entry DOI: 10.7270/Q2CV4JG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (MOUSE) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 703 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Binding affinity was measured in cloned Opioid receptor delta 1 expressed in CHO cells using [3H]- DPDPE as radioligand. | J Med Chem 43: 3941-8 (2000) BindingDB Entry DOI: 10.7270/Q2CV4JG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 116 | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inverse agonist activity at human DOR expressed in CHO cell membranes by [35S]GTPgammaS binding assay | Bioorg Med Chem Lett 25: 2927-30 (2015) BindingDB Entry DOI: 10.7270/Q28C9Z0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (MOUSE) | BDBM50006946 (2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Tested for agonist activity against delta opioid receptor mouse vas deferens | J Med Chem 37: 2125-8 (1994) BindingDB Entry DOI: 10.7270/Q2ZG6SWK | |||||||||||
More data for this Ligand-Target Pair |