BDBM50006987 CHEMBL55769::N-Adamantan-1-yl-N'-(3-iodo-phenyl)-guanidine

SMILES: NC(Nc1cccc(I)c1)=NC12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=TVIJTHHQQPCCQG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50006987 (CHEMBL55769 | N-Adamantan-1-yl-N'-(3-iodo-phenyl)-...) Show SMILES NC(Nc1cccc(I)c1)=NC12CC3CC(CC(C3)C1)C2 |w:10.11,TLB:14:15:19:13.12.18,THB:14:13:19:15.20.16,16:15:12:17.19.18,16:17:12:15.20.14| Show InChI InChI=1S/C17H22IN3/c18-14-2-1-3-15(7-14)20-16(19)21-17-8-11-4-12(9-17)6-13(5-11)10-17/h1-3,7,11-13H,4-6,8-10H2,(H3,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Institutions Curated by ChEMBL					Assay Description Displacement of [3H]-DTG from sigma opioid receptor of homogenized guinea pig whole brain				J Med Chem 34: 1867-70 (1991) BindingDB Entry DOI: 10.7270/Q21N802D
					More data for this Ligand-Target Pair