BDBM50007175 Adamantane-1-carboxylic acid [4-(4-naphthalen-1-yl-piperazin-1-yl)-butyl]-amide::CHEMBL410826

SMILES: O=C(NCCCCN1CCN(CC1)c1cccc2ccccc12)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2

InChI Key: InChIKey=SDFJEQNUYLCLFY-DYIAZFBVSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50007175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50007175 (Adamantane-1-carboxylic acid [4-(4-naphthalen-1-yl...) Show SMILES O=C(NCCCCN1CCN(CC1)c1cccc2ccccc12)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 |THB:28:29:24:32.27.26,28:27:24:31.29.30| Show InChI InChI=1S/C29H39N3O/c33-28(29-19-22-16-23(20-29)18-24(17-22)21-29)30-10-3-4-11-31-12-14-32(15-13-31)27-9-5-7-25-6-1-2-8-26(25)27/h1-2,5-9,22-24H,3-4,10-21H2,(H,30,33)/t22-,23+,24-,29?	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor of rat hippocampus using [3H]-8-hydroxy-2-(di-n-propylamine) tetralin (8-OH-DPAT) as a radio...				J Med Chem 34: 2633-8 (1991) BindingDB Entry DOI: 10.7270/Q2833R0C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50007175 (Adamantane-1-carboxylic acid [4-(4-naphthalen-1-yl...) Show SMILES O=C(NCCCCN1CCN(CC1)c1cccc2ccccc12)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 |THB:28:29:24:32.27.26,28:27:24:31.29.30| Show InChI InChI=1S/C29H39N3O/c33-28(29-19-22-16-23(20-29)18-24(17-22)21-29)30-10-3-4-11-31-12-14-32(15-13-31)27-9-5-7-25-6-1-2-8-26(25)27/h1-2,5-9,22-24H,3-4,10-21H2,(H,30,33)/t22-,23+,24-,29?	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.708	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lausanne Curated by ChEMBL					Assay Description Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacement				J Med Chem 39: 126-34 (1996) Article DOI: 10.1021/jm950410b BindingDB Entry DOI: 10.7270/Q2VX0K7V
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50007175 (Adamantane-1-carboxylic acid [4-(4-naphthalen-1-yl...) Show SMILES O=C(NCCCCN1CCN(CC1)c1cccc2ccccc12)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 |THB:28:29:24:32.27.26,28:27:24:31.29.30| Show InChI InChI=1S/C29H39N3O/c33-28(29-19-22-16-23(20-29)18-24(17-22)21-29)30-10-3-4-11-31-12-14-32(15-13-31)27-9-5-7-25-6-1-2-8-26(25)27/h1-2,5-9,22-24H,3-4,10-21H2,(H,30,33)/t22-,23+,24-,29?	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor of rat frontal cortex using [3H]- WB- 4101 as a radioligand				J Med Chem 34: 2633-8 (1991) BindingDB Entry DOI: 10.7270/Q2833R0C
					More data for this Ligand-Target Pair