BDBM50007423 (R)6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrobromide::CHEMBL318111::CHEMBL542493::cid_11957524

SMILES: Oc1ccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c2c1O

InChI Key: InChIKey=XEXUKNQDDPKEIF-OAHLLOKOSA-N

Data: 6 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50007423   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007423 ((R)6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qui...) Show SMILES Oc1ccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C19H19NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h2-7,15,21-22H,1,8-11H2/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit Dopamine receptor D2 in rat striatum using [3H]spiperone				J Med Chem 34: 24-8 (1991) BindingDB Entry DOI: 10.7270/Q24Q7VKQ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007423 ((R)6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qui...) Show SMILES Oc1ccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C19H19NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h2-7,15,21-22H,1,8-11H2/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D2 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50007423 ((R)6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qui...) Show SMILES Oc1ccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C19H19NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h2-7,15,21-22H,1,8-11H2/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Agonist activity was tested in vitro against Dopamine receptor from rat brain membranes with [3H]ADT-6,7-dihydroxy-2-aminotetralin]				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50007423 ((R)6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qui...) Show SMILES Oc1ccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C19H19NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h2-7,15,21-22H,1,8-11H2/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit Striatal Dopamine receptor in rat brain through radioreceptor assay carried out with agonist ligand...				J Med Chem 34: 24-8 (1991) BindingDB Entry DOI: 10.7270/Q24Q7VKQ
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50007423 ((R)6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qui...) Show SMILES Oc1ccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C19H19NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h2-7,15,21-22H,1,8-11H2/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	615	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D1 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50007423 ((R)6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qui...) Show SMILES Oc1ccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C19H19NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h2-7,15,21-22H,1,8-11H2/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	617	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit Dopamine receptor D1 in rat striatum using [3H]SCH-23390				J Med Chem 34: 24-8 (1991) BindingDB Entry DOI: 10.7270/Q24Q7VKQ
					More data for this Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b (Homo sapiens (Human))	BDBM50007423 ((R)6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qui...) Show SMILES Oc1ccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C19H19NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h2-7,15,21-22H,1,8-11H2/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q280513R
					More data for this Ligand-Target Pair
Hsf1 protein (Mus musculus)	BDBM50007423 ((R)6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qui...) Show SMILES Oc1ccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C19H19NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h2-7,15,21-22H,1,8-11H2/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	>2.60E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2P55KXK
					More data for this Ligand-Target Pair