BDBM50007538 8-(2-Azetidin-1-yl-ethyl)-3-chloro-6-methyl-7,8-dihydro-6H-9-oxa-1,6-diaza-benzocycloheptene-5-thione::CHEMBL25626

SMILES: CN1C[C@@H](CCN2CCC2)Oc2ncc(Cl)cc2C1=S

InChI Key: InChIKey=TTZNDWMUJXPGIQ-LLVKDONJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007538   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50007538 (8-(2-Azetidin-1-yl-ethyl)-3-chloro-6-methyl-7,8-di...) Show SMILES CN1C[C@@H](CCN2CCC2)Oc2ncc(Cl)cc2C1=S Show InChI InChI=1S/C14H18ClN3OS/c1-17-9-11(3-6-18-4-2-5-18)19-13-12(14(17)20)7-10(15)8-16-13/h7-8,11H,2-6,9H2,1H3/t11-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
A. H. Robins Company, Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-mepyramine binding to the histamine receptor in guinea pig cortex				J Med Chem 34: 1314-28 (1991) BindingDB Entry DOI: 10.7270/Q23F4NMG
					More data for this Ligand-Target Pair