null

SMILES: CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1[C@@H]([C@H](O[C@H](CC(O)=O)C1=O)c1cccc(Cl)c1)c1ccc(Cl)cc1

InChI Key: InChIKey=KMAGOCXNUIXUMN-CLOIUZTFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007640   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50007640 (CHEMBL3233121) Show SMILES CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1[C@@H]([C@H](O[C@H](CC(O)=O)C1=O)c1cccc(Cl)c1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C26H30Cl2N2O6S/c1-3-20(15-29(2)37(34,35)21-11-12-21)30-24(16-7-9-18(27)10-8-16)25(17-5-4-6-19(28)13-17)36-22(26(30)33)14-23(31)32/h4-10,13,20-22,24-25H,3,11-12,14-15H2,1-2H3,(H,31,32)/t20-,22+,24+,25+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in buffer ...				J Med Chem 57: 2472-88 (2014) Article DOI: 10.1021/jm401767k BindingDB Entry DOI: 10.7270/Q2C24XZZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50007640 (CHEMBL3233121) Show SMILES CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1[C@@H]([C@H](O[C@H](CC(O)=O)C1=O)c1cccc(Cl)c1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C26H30Cl2N2O6S/c1-3-20(15-29(2)37(34,35)21-11-12-21)30-24(16-7-9-18(27)10-8-16)25(17-5-4-6-19(28)13-17)36-22(26(30)33)14-23(31)32/h4-10,13,20-22,24-25H,3,11-12,14-15H2,1-2H3,(H,31,32)/t20-,22+,24+,25+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in serum f...				J Med Chem 57: 2472-88 (2014) Article DOI: 10.1021/jm401767k BindingDB Entry DOI: 10.7270/Q2C24XZZ
					More data for this Ligand-Target Pair