null

SMILES: NC(=N)c1ccc(cc1)-c1ccc(o1)-c1ccc(nc1)C(N)=N

InChI Key: InChIKey=IFAJVIYMOBCWOU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50007728   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 1 [11-371] (Homo sapiens (Human))	BDBM50007728 (CHEMBL424121 | DB867) Show SMILES NC(=N)c1ccc(cc1)-c1ccc(o1)-c1ccc(nc1)C(N)=N Show InChI InChI=1S/C17H15N5O/c18-16(19)11-3-1-10(2-4-11)14-7-8-15(23-14)12-5-6-13(17(20)21)22-9-12/h1-9H,(H3,18,19)(H3,20,21)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of His6x-tagged recombinant PRMT1 (unknown origin) expressed in Escherichia coli BL21(DE3) using [3H]SAM and histone H4 (1 to 20) as subst...				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50007728 (CHEMBL424121 | DB867) Show SMILES NC(=N)c1ccc(cc1)-c1ccc(o1)-c1ccc(nc1)C(N)=N Show InChI InChI=1S/C17H15N5O/c18-16(19)11-3-1-10(2-4-11)14-7-8-15(23-14)12-5-6-13(17(20)21)22-9-12/h1-9H,(H3,18,19)(H3,20,21)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of His6x-tagged PRMT6 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assay				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
					More data for this Ligand-Target Pair
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50007728 (CHEMBL424121 | DB867) Show SMILES NC(=N)c1ccc(cc1)-c1ccc(o1)-c1ccc(nc1)C(N)=N Show InChI InChI=1S/C17H15N5O/c18-16(19)11-3-1-10(2-4-11)14-7-8-15(23-14)12-5-6-13(17(20)21)22-9-12/h1-9H,(H3,18,19)(H3,20,21)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of GST-tagged CARM1 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assay				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM50007728 (CHEMBL424121 | DB867) Show SMILES NC(=N)c1ccc(cc1)-c1ccc(o1)-c1ccc(nc1)C(N)=N Show InChI InChI=1S/C17H15N5O/c18-16(19)11-3-1-10(2-4-11)14-7-8-15(23-14)12-5-6-13(17(20)21)22-9-12/h1-9H,(H3,18,19)(H3,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.86E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of HA-tagged recombinant PRMT5 (unknown origin) expressed in HEK293T cells using [3H]SAM and histone H4 (1 to 20) as substrate after 8 min...				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
					More data for this Ligand-Target Pair