BDBM50007735 CHEMBL3233486

SMILES: CCNC(=O)c1noc2CCN(Cc12)C(=O)c1cc(Cl)c(O)cc1O

InChI Key: InChIKey=CJZPIANKAUZKQG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007735   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock protein HSP 90-alpha (Homo sapiens (Human))	BDBM50007735 (CHEMBL3233486) Show SMILES CCNC(=O)c1noc2CCN(Cc12)C(=O)c1cc(Cl)c(O)cc1O Show InChI InChI=1S/C16H16ClN3O5/c1-2-18-15(23)14-9-7-20(4-3-13(9)25-19-14)16(24)8-5-10(17)12(22)6-11(8)21/h5-6,21-22H,2-4,7H2,1H3,(H,18,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Ferrara Curated by ChEMBL					Assay Description Displacement of GM-FTC from Hsp90-alpha (unknown origin) after 4 hrs by fluorescence polarization assay				Eur J Med Chem 76: 53-60 (2014) Article DOI: 10.1016/j.ejmech.2014.01.056 BindingDB Entry DOI: 10.7270/Q2V40WQX
					More data for this Ligand-Target Pair