BDBM50007747 CHEMBL3233757

SMILES: CCC(CC)C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2s1

InChI Key: InChIKey=DDKCGPPPROXNNF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50007747 (CHEMBL3233757) Show SMILES CCC(CC)C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2s1 Show InChI InChI=1S/C18H18ClFN4OS/c1-3-10(4-2)17(25)24-15-8-12-16(21-9-22-18(12)26-15)23-11-5-6-14(20)13(19)7-11/h5-10H,3-4H2,1-2H3,(H,24,25)(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of wild type EGFR domain (unknown origin) expressed in baculovirus expression system using Poly(Glu:Tyr)4:1 substrate after 60 mins by ELI...				Bioorg Med Chem 22: 2366-78 (2014) Article DOI: 10.1016/j.bmc.2014.01.035 BindingDB Entry DOI: 10.7270/Q2QC051F
					More data for this Ligand-Target Pair