BDBM50007761 CHEMBL3233771

SMILES: COCCNC\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2s1

InChI Key: InChIKey=IACLWEVYVPVQAK-NSCUHMNNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50007761 (CHEMBL3233771) Show SMILES COCCNC\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2s1 Show InChI InChI=1S/C19H19ClFN5O2S/c1-28-8-7-22-6-2-3-16(27)26-17-10-13-18(23-11-24-19(13)29-17)25-12-4-5-15(21)14(20)9-12/h2-5,9-11,22H,6-8H2,1H3,(H,26,27)(H,23,24,25)/b3-2+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of wild type EGFR domain (unknown origin) expressed in baculovirus expression system using Poly(Glu:Tyr)4:1 substrate after 60 mins by ELI...				Bioorg Med Chem 22: 2366-78 (2014) Article DOI: 10.1016/j.bmc.2014.01.035 BindingDB Entry DOI: 10.7270/Q2QC051F
					More data for this Ligand-Target Pair