BDBM50007764 CHEMBL3233774

SMILES: Fc1ccc(Nc2ncnc3sc(NC(=O)\C=C\CNCC4COC4)cc23)cc1Cl

InChI Key: InChIKey=HLSRBPGSLVXDKF-OWOJBTEDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007764   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50007764 (CHEMBL3233774) Show SMILES Fc1ccc(Nc2ncnc3sc(NC(=O)\C=C\CNCC4COC4)cc23)cc1Cl Show InChI InChI=1S/C20H19ClFN5O2S/c21-15-6-13(3-4-16(15)22)26-19-14-7-18(30-20(14)25-11-24-19)27-17(28)2-1-5-23-8-12-9-29-10-12/h1-4,6-7,11-12,23H,5,8-10H2,(H,27,28)(H,24,25,26)/b2-1+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of wild type EGFR domain (unknown origin) expressed in baculovirus expression system using Poly(Glu:Tyr)4:1 substrate after 60 mins by ELI...				Bioorg Med Chem 22: 2366-78 (2014) Article DOI: 10.1016/j.bmc.2014.01.035 BindingDB Entry DOI: 10.7270/Q2QC051F
					More data for this Ligand-Target Pair