null

SMILES: CCOC(=O)NC(=S)N(CC(=O)c1ccc(Cl)cc1)c1ccc(cc1)S(N)(=O)=O

InChI Key: InChIKey=RZSDFRUJNZFUDN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50008343   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50008343 (CHEMBL3235172) Show SMILES CCOC(=O)NC(=S)N(CC(=O)c1ccc(Cl)cc1)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H18ClN3O5S2/c1-2-27-18(24)21-17(28)22(11-16(23)12-3-5-13(19)6-4-12)14-7-9-15(10-8-14)29(20,25)26/h3-10H,2,11H2,1H3,(H2,20,25,26)(H,21,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra...				Bioorg Med Chem Lett 24: 1776-9 (2014) Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50008343 (CHEMBL3235172) Show SMILES CCOC(=O)NC(=S)N(CC(=O)c1ccc(Cl)cc1)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H18ClN3O5S2/c1-2-27-18(24)21-17(28)22(11-16(23)12-3-5-13(19)6-4-12)14-7-9-15(10-8-14)29(20,25)26/h3-10H,2,11H2,1H3,(H2,20,25,26)(H,21,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras...				Bioorg Med Chem Lett 24: 1776-9 (2014) Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50008343 (CHEMBL3235172) Show SMILES CCOC(=O)NC(=S)N(CC(=O)c1ccc(Cl)cc1)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H18ClN3O5S2/c1-2-27-18(24)21-17(28)22(11-16(23)12-3-5-13(19)6-4-12)14-7-9-15(10-8-14)29(20,25)26/h3-10H,2,11H2,1H3,(H2,20,25,26)(H,21,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay				Bioorg Med Chem Lett 24: 1776-9 (2014) Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50008343 (CHEMBL3235172) Show SMILES CCOC(=O)NC(=S)N(CC(=O)c1ccc(Cl)cc1)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H18ClN3O5S2/c1-2-27-18(24)21-17(28)22(11-16(23)12-3-5-13(19)6-4-12)14-7-9-15(10-8-14)29(20,25)26/h3-10H,2,11H2,1H3,(H2,20,25,26)(H,21,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	593	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay				Bioorg Med Chem Lett 24: 1776-9 (2014) Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6
					More data for this Ligand-Target Pair