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BDBM50008356 5-(2-(diethylamino)ethylamino)-8-methoxy-1-methyl-6H-imidazo[4,5,1-de]acridin-6-one::5-(2-Diethylamino-ethylamino)-8-methoxy-1-methyl-2,10b-diaza-aceanthrylen-6-one(2.0MHCl)::CHEMBL124254::NSC-637993

SMILES: CCN(CC)CCNc1ccc2nc(C)n3c2c1c(=O)c1cc(OC)ccc31

InChI Key: InChIKey=URGOPTXSJQVCSA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008356   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosyldihydronicotinamide dehydrogenase [quinone]


(Homo sapiens (Human))
BDBM50008356
PNG
(5-(2-(diethylamino)ethylamino)-8-methoxy-1-methyl-...)
Show SMILES CCN(CC)CCNc1ccc2nc(C)n3c2c1c(=O)c1cc(OC)ccc31
Show InChI InChI=1S/C22H26N4O2/c1-5-25(6-2)12-11-23-17-8-9-18-21-20(17)22(27)16-13-15(28-4)7-10-19(16)26(21)14(3)24-18/h7-10,13,23H,5-6,11-12H2,1-4H3
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MMDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 9n/an/an/an/an/an/a



the University of Manchester and Manchester Cancer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry


Bioorg Med Chem Lett 20: 2832-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.051
BindingDB Entry DOI: 10.7270/Q2FB533K
More data for this
Ligand-Target Pair