BDBM50008390 CHEMBL3235188

SMILES: CC(=O)c1sc(NC(=O)Cc2cccc(Cl)c2)nc1C

InChI Key: InChIKey=PVIGHKTVSXASBO-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008390   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50008390 (CHEMBL3235188) Show SMILES CC(=O)c1sc(NC(=O)Cc2cccc(Cl)c2)nc1C Show InChI InChI=1S/C14H13ClN2O2S/c1-8-13(9(2)18)20-14(16-8)17-12(19)7-10-4-3-5-11(15)6-10/h3-6H,7H2,1-2H3,(H,16,17,19)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay				J Med Chem 57: 2755-72 (2014) Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV
					More data for this Ligand-Target Pair