BDBM50008398 CHEMBL3235534

SMILES: COc1ccc(NC(=O)Nc2nc3ccc(cc3s2)C(F)(F)F)cc1

InChI Key: InChIKey=SLPPRPLXTJJDSU-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008398   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50008398 (CHEMBL3235534) Show SMILES COc1ccc(NC(=O)Nc2nc3ccc(cc3s2)C(F)(F)F)cc1 Show InChI InChI=1S/C16H12F3N3O2S/c1-24-11-5-3-10(4-6-11)20-14(23)22-15-21-12-7-2-9(16(17,18)19)8-13(12)25-15/h2-8H,1H3,(H2,20,21,22,23)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay				J Med Chem 57: 2755-72 (2014) Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV
					More data for this Ligand-Target Pair