BDBM50008785 CHEMBL42953::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-(3-fluoro-propyl)-2,3-dimethoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-(3-fluoro-propyl)-2,3-dimethoxy-benzamide (FP-epidepride)

SMILES: CCN1CCC[C@H]1CNC(=O)c1cc(CCCF)cc(OC)c1OC

InChI Key: InChIKey=CRDCKDWZBHLFAS-HNNXBMFYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008785   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50008785 (CHEMBL42953 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-...) Show SMILES CCN1CCC[C@H]1CNC(=O)c1cc(CCCF)cc(OC)c1OC Show InChI InChI=1S/C19H29FN2O3/c1-4-22-10-6-8-15(22)13-21-19(23)16-11-14(7-5-9-20)12-17(24-2)18(16)25-3/h11-12,15H,4-10,13H2,1-3H3,(H,21,23)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition constant against dopamine receptor D2 in rat				J Med Chem 36: 221-8 (1993) BindingDB Entry DOI: 10.7270/Q2TT4Q10
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50008785 (CHEMBL42953 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-...) Show SMILES CCN1CCC[C@H]1CNC(=O)c1cc(CCCF)cc(OC)c1OC Show InChI InChI=1S/C19H29FN2O3/c1-4-22-10-6-8-15(22)13-21-19(23)16-11-14(7-5-9-20)12-17(24-2)18(16)25-3/h11-12,15H,4-10,13H2,1-3H3,(H,21,23)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity towards dopamine receptor D2 in striatal membranes, using [3H]- spiperone as radioligand in the presence ...				J Med Chem 34: 1612-24 (1991) BindingDB Entry DOI: 10.7270/Q2GH9GXF
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50008785 (CHEMBL42953 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-...) Show SMILES CCN1CCC[C@H]1CNC(=O)c1cc(CCCF)cc(OC)c1OC Show InChI InChI=1S/C19H29FN2O3/c1-4-22-10-6-8-15(22)13-21-19(23)16-11-14(7-5-9-20)12-17(24-2)18(16)25-3/h11-12,15H,4-10,13H2,1-3H3,(H,21,23)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity towards dopamine receptor D2 in striatal membranes, using [3H]- spiperone as radioligand in the presence ...				J Med Chem 34: 1612-24 (1991) BindingDB Entry DOI: 10.7270/Q2GH9GXF
					More data for this Ligand-Target Pair