null
SMILES: CC1C(C(=O)N(C)[C@H]2CCC3(CCCO3)C[C@@H]2N2CCCC2)c2cccc3cccc1c23
InChI Key: InChIKey=XWROGPXUCYJQLL-VUPKEGFWSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50008856 (2-Methyl-acenaphthene-1-carboxylic acid methyl-(7-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin | J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM50008856 (2-Methyl-acenaphthene-1-carboxylic acid methyl-(7-...) | UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 244 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u... | J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50008856 (2-Methyl-acenaphthene-1-carboxylic acid methyl-(7-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 578 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Compound was evaluated for the opioid receptor delta affinity | J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG | |||||||||||
More data for this Ligand-Target Pair |