BDBM50008987 2-(5-Bromo-pyridin-3-ylmethyl)-1,2-dihydro-indazol-3-one::CHEMBL3144584::CHEMBL8430

SMILES: Brc1cncc(Cn2[nH]c3ccccc3c2=O)c1

InChI Key: InChIKey=XEXXJJDEIDKQEY-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50008987 (2-(5-Bromo-pyridin-3-ylmethyl)-1,2-dihydro-indazol...) Show SMILES Brc1cncc(Cn2[nH]c3ccccc3c2=O)c1 Show InChI InChI=1S/C13H10BrN3O/c14-10-5-9(6-15-7-10)8-17-13(18)11-3-1-2-4-12(11)16-17/h1-7,16H,8H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharma Curated by ChEMBL					Assay Description In vitro inhibition of LTB4 production was measured in rat blood				J Med Chem 34: 1028-36 (1991) BindingDB Entry DOI: 10.7270/Q28G8MXH
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50008987 (2-(5-Bromo-pyridin-3-ylmethyl)-1,2-dihydro-indazol...) Show SMILES Brc1cncc(Cn2[nH]c3ccccc3c2=O)c1 Show InChI InChI=1S/C13H10BrN3O/c14-10-5-9(6-15-7-10)8-17-13(18)11-3-1-2-4-12(11)16-17/h1-7,16H,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
ICI Pharma Curated by ChEMBL					Assay Description Ex vivo inhibition of LTB4 production was measured in dog blood				J Med Chem 34: 1028-36 (1991) BindingDB Entry DOI: 10.7270/Q28G8MXH
					More data for this Ligand-Target Pair
Cyclooxygenase (RAT)	BDBM50008987 (2-(5-Bromo-pyridin-3-ylmethyl)-1,2-dihydro-indazol...) Show SMILES Brc1cncc(Cn2[nH]c3ccccc3c2=O)c1 Show InChI InChI=1S/C13H10BrN3O/c14-10-5-9(6-15-7-10)8-17-13(18)11-3-1-2-4-12(11)16-17/h1-7,16H,8H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharma Curated by ChEMBL					Assay Description In vitro inhibition of PGE-2 production was measured in rat blood				J Med Chem 34: 1028-36 (1991) BindingDB Entry DOI: 10.7270/Q28G8MXH
					More data for this Ligand-Target Pair