BDBM50009011 2-(5-Methyl-pyridin-3-ylmethyl)-1,2-dihydro-indazol-3-one::CHEMBL273253::CHEMBL3144722

SMILES: Cc1cncc(Cn2[nH]c3ccccc3c2=O)c1

InChI Key: InChIKey=WOXLDLWZGLWCLI-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50009011 (2-(5-Methyl-pyridin-3-ylmethyl)-1,2-dihydro-indazo...) Show SMILES Cc1cncc(Cn2[nH]c3ccccc3c2=O)c1 Show InChI InChI=1S/C14H13N3O/c1-10-6-11(8-15-7-10)9-17-14(18)12-4-2-3-5-13(12)16-17/h2-8,16H,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharma Curated by ChEMBL					Assay Description In vitro inhibition of LTB4 production was measured in rat blood				J Med Chem 34: 1028-36 (1991) BindingDB Entry DOI: 10.7270/Q28G8MXH
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50009011 (2-(5-Methyl-pyridin-3-ylmethyl)-1,2-dihydro-indazo...) Show SMILES Cc1cncc(Cn2[nH]c3ccccc3c2=O)c1 Show InChI InChI=1S/C14H13N3O/c1-10-6-11(8-15-7-10)9-17-14(18)12-4-2-3-5-13(12)16-17/h2-8,16H,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
ICI Pharma Curated by ChEMBL					Assay Description Ex vivo inhibition of LTB4 production was measured in dog blood				J Med Chem 34: 1028-36 (1991) BindingDB Entry DOI: 10.7270/Q28G8MXH
					More data for this Ligand-Target Pair
Cyclooxygenase (RAT)	BDBM50009011 (2-(5-Methyl-pyridin-3-ylmethyl)-1,2-dihydro-indazo...) Show SMILES Cc1cncc(Cn2[nH]c3ccccc3c2=O)c1 Show InChI InChI=1S/C14H13N3O/c1-10-6-11(8-15-7-10)9-17-14(18)12-4-2-3-5-13(12)16-17/h2-8,16H,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharma Curated by ChEMBL					Assay Description In vitro inhibition of PGE-2 production was measured in rat blood				J Med Chem 34: 1028-36 (1991) BindingDB Entry DOI: 10.7270/Q28G8MXH
					More data for this Ligand-Target Pair