BDBM50009101 4-Benzyloxy-1H-indole-2-carboxylic acid::CHEMBL23399
SMILES: OC(=O)c1cc2c(OCc3ccccc3)cccc2[nH]1
InChI Key: InChIKey=GSXFWBDVTDHJFZ-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Steroid 5-alpha-reductase (Homo sapiens (Human)) | BDBM50009101 (4-Benzyloxy-1H-indole-2-carboxylic acid | CHEMBL23...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition constant against recombinant human Steroid 5-alpha-reductase type 2 expressed in CHO cells | J Med Chem 38: 13-5 (1995) BindingDB Entry DOI: 10.7270/Q2D50P5K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5α-Reductase 1 (5α-R1) (Homo sapiens (Human)) | BDBM50009101 (4-Benzyloxy-1H-indole-2-carboxylic acid | CHEMBL23...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Apparent inhibition constant against recombinant human Steroid 5-alpha-reductase type I expressed in CHO cells | J Med Chem 38: 13-5 (1995) BindingDB Entry DOI: 10.7270/Q2D50P5K | |||||||||||
More data for this Ligand-Target Pair |