BDBM50009210 CHEMBL3233153

SMILES: Cn1c(CN2CC(=O)N(CC2=O)c2ccc(Oc3ccccc3)cc2)cc2cnc(nc12)C(=O)N[C@@H](CCCCN)C#N

InChI Key: InChIKey=LQTYLIHKDZLCLN-QFIPXVFZSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen (Homo sapiens (Human))	BDBM50009210 (CHEMBL3233153) Show SMILES Cn1c(CN2CC(=O)N(CC2=O)c2ccc(Oc3ccccc3)cc2)cc2cnc(nc12)C(=O)N[C@@H](CCCCN)C#N |r| Show InChI InChI=1S/C31H32N8O4/c1-37-24(15-21-17-34-29(36-30(21)37)31(42)35-22(16-33)7-5-6-14-32)18-38-19-28(41)39(20-27(38)40)23-10-12-26(13-11-23)43-25-8-3-2-4-9-25/h2-4,8-13,15,17,22H,5-7,14,18-20,32H2,1H3,(H,35,42)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hiroshima International University Curated by ChEMBL					Assay Description Inhibition of human plasmin using H-D-Val-Leu-LyspNA (S-2251) peptide as substrate assessed as reduction of enzyme hydrolytic activity				Bioorg Med Chem 22: 2339-52 (2014) Article DOI: 10.1016/j.bmc.2014.02.002 BindingDB Entry DOI: 10.7270/Q2KH0PVJ
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50009210 (CHEMBL3233153) Show SMILES Cn1c(CN2CC(=O)N(CC2=O)c2ccc(Oc3ccccc3)cc2)cc2cnc(nc12)C(=O)N[C@@H](CCCCN)C#N |r| Show InChI InChI=1S/C31H32N8O4/c1-37-24(15-21-17-34-29(36-30(21)37)31(42)35-22(16-33)7-5-6-14-32)18-38-19-28(41)39(20-27(38)40)23-10-12-26(13-11-23)43-25-8-3-2-4-9-25/h2-4,8-13,15,17,22H,5-7,14,18-20,32H2,1H3,(H,35,42)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Hiroshima International University Curated by ChEMBL					Assay Description Inhibition of human plasma urokinase using Glu-Gly-Arg-pNA (S-2444) peptide as substrate assessed as reduction of enzyme hydrolytic activity				Bioorg Med Chem 22: 2339-52 (2014) Article DOI: 10.1016/j.bmc.2014.02.002 BindingDB Entry DOI: 10.7270/Q2KH0PVJ
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM50009210 (CHEMBL3233153) Show SMILES Cn1c(CN2CC(=O)N(CC2=O)c2ccc(Oc3ccccc3)cc2)cc2cnc(nc12)C(=O)N[C@@H](CCCCN)C#N |r| Show InChI InChI=1S/C31H32N8O4/c1-37-24(15-21-17-34-29(36-30(21)37)31(42)35-22(16-33)7-5-6-14-32)18-38-19-28(41)39(20-27(38)40)23-10-12-26(13-11-23)43-25-8-3-2-4-9-25/h2-4,8-13,15,17,22H,5-7,14,18-20,32H2,1H3,(H,35,42)/t22-/m0/s1	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Hiroshima International University Curated by ChEMBL					Assay Description Inhibition of human plasma kallikerin using H-D-Phe-Pro-Arg-pNA (S-2302) peptide as substrate assessed as reduction of enzyme hydrolytic activity				Bioorg Med Chem 22: 2339-52 (2014) Article DOI: 10.1016/j.bmc.2014.02.002 BindingDB Entry DOI: 10.7270/Q2KH0PVJ
					More data for this Ligand-Target Pair