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SMILES: COc1nc(F)nc(OC)c1NC(=O)c1ccc(Oc2cc3c(CCC3(C)C)cc2C)o1

InChI Key: InChIKey=ZPYIKASOCBNKOR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50009297   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)		BDBM50009297
PNG
(CHEMBL3233520)
Show SMILES COc1nc(F)nc(OC)c1NC(=O)c1ccc(Oc2cc3c(CCC3(C)C)cc2C)o1
Show InChI InChI=1S/C23H24FN3O5/c1-12-10-13-8-9-23(2,3)14(13)11-16(12)32-17-7-6-15(31-17)19(28)25-18-20(29-4)26-22(24)27-21(18)30-5/h6-7,10-11H,8-9H2,1-5H3,(H,25,28)
KEGG

UniProtKB/SwissProt

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PC sid
UniChem

Similars
Article
PubMed
 42n/an/an/an/an/an/an/an/a



Norwegian Medical Cyclotron Centre, PO Box 4950, Nydalen, N-0424 Oslo, Norway.

Curated by ChEMBL


Assay Description
Displacement of [125I]Triptorelin from rat full-length gonadotropin-releasing hormone receptor expressed in HEK293 cells

Bioorg Med Chem Lett 24: 1846-50 (2014)


Article DOI: 10.1016/j.bmcl.2014.02.002
BindingDB Entry DOI: 10.7270/Q2XS5WXP
More data for this
Ligand-Target Pair