BDBM50009304 CHEMBL3233531
SMILES: OCC[C@@H]1CN(CC2CCCCC2)CCN1Cc1cccc2ccccc12
InChI Key: InChIKey=TZAWKCIVGVDWDQ-HSZRJFAPSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig)) | BDBM50009304 (CHEMBL3233531) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of M£nster Curated by ChEMBL | Assay Description Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting analysis | J Med Chem 57: 2884-94 (2014) Article DOI: 10.1021/jm401707t BindingDB Entry DOI: 10.7270/Q2T15562 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50009304 (CHEMBL3233531) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of M£nster Curated by ChEMBL | Assay Description Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human RPMI8226 cell membranes after 120 mins by scintillation counting analysis | J Med Chem 57: 2884-94 (2014) Article DOI: 10.1021/jm401707t BindingDB Entry DOI: 10.7270/Q2T15562 | |||||||||||
More data for this Ligand-Target Pair |