Found 19 hits for monomerid = 50009353 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Glutamate receptor ionotropic, NMDA 1
(RAT) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | PDB
UniProtKB/SwissProt
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| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd.
Curated by PDSP Ki Database
| |
J Neurochem 70: 2147-55 (1998)
Article DOI: 10.1046/j.1471-4159.1998.70052147.x BindingDB Entry DOI: 10.7270/Q2KP80Q7 |
More data for this Ligand-Target Pair | |
Pyruvate kinase PKM
(Homo sapiens (Human)) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | PDB
KEGG
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 1.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00981 BindingDB Entry DOI: 10.7270/Q2M330SP |
More data for this Ligand-Target Pair | |
Ornithine decarboxylase
(Rattus norvegicus) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
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| 2.70E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Competitive inhibition of Sprague-Dawley rat prostate ornithine decarboxylase using DL-[1-14C]ornithine as substrate by liquid scintillation counting... |
J Med Chem 21: 50-5 (1978)
BindingDB Entry DOI: 10.7270/Q2BR8TQP |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
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| 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 1 by stopped flow CO2 hydration method |
J Med Chem 53: 5511-22 (2010)
Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | PDB MMDB
Reactome pathway KEGG
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| 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 by stopped flow CO2 hydration method |
J Med Chem 53: 5511-22 (2010)
Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 3
(Homo sapiens (Human)) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | PDB MMDB
Reactome pathway KEGG
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| 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration method |
J Med Chem 53: 5511-22 (2010)
Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Homo sapiens (Human)) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | PDB MMDB
Reactome pathway KEGG
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| 112 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration method |
J Med Chem 53: 5511-22 (2010)
Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | Reactome pathway KEGG
UniProtKB/SwissProt
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| 1.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 5A by stopped flow CO2 hydration method |
J Med Chem 53: 5511-22 (2010)
Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 5B, mitochondrial
(Homo sapiens (Human)) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | Reactome pathway KEGG
UniProtKB/SwissProt
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| 1.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 5B by stopped flow CO2 hydration method |
J Med Chem 53: 5511-22 (2010)
Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 6
(Homo sapiens (Human)) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | PDB
UniProtKB/SwissProt
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| 1.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 6 by stopped flow CO2 hydration method |
J Med Chem 53: 5511-22 (2010)
Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 7
(Homo sapiens (Human)) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | PDB MMDB
Reactome pathway KEGG
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| 1.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration method |
J Med Chem 53: 5511-22 (2010)
Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
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| 1.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 by stopped flow CO2 hydration method |
J Med Chem 53: 5511-22 (2010)
Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| 4.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydration method |
J Med Chem 53: 5511-22 (2010)
Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 13
(Mus musculus (mouse)) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | PDB MMDB
Reactome pathway KEGG
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| 1.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of mouse carbonic anhydrase 13 by stopped flow CO2 hydration method |
J Med Chem 53: 5511-22 (2010)
Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 14
(Homo sapiens (Human)) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| Article PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration method |
J Med Chem 53: 5511-22 (2010)
Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 15
(Mus musculus) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | KEGG
UniProtKB/SwissProt
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| Article PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of mouse carbonic anhydrase 15 by stopped flow CO2 hydration method |
J Med Chem 53: 5511-22 (2010)
Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB |
More data for this Ligand-Target Pair | |
DNA topoisomerase 2-alpha
(Homo sapiens (Human)) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | PDB
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy; Laboratory of Molecular Modeling and Drug Discovery, Istituto Italiano di
Curated by ChEMBL
| Assay Description Inhibition of recombinant human topoisomerase-2alpha expressed in Saccharomyces cerevisiae JEL1 harboring topoisomerase1 deletion mutant assessed as ... |
Bioorg Med Chem Lett 27: 4687-4693 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.011 BindingDB Entry DOI: 10.7270/Q21R6T0Q |
More data for this Ligand-Target Pair | |
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B
(Bos taurus-BOVINE) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | PDB
KEGG
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesterase |
J Med Chem 49: 232-45 (2006)
Article DOI: 10.1021/jm050018q BindingDB Entry DOI: 10.7270/Q21Z4757 |
More data for this Ligand-Target Pair | |
Ornithine decarboxylase
(Bos taurus) | BDBM50009353
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 | PDB MMDB
KEGG
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| 3.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Competitive inhibition of bull prostate ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysis |
J Med Chem 21: 50-5 (1978)
BindingDB Entry DOI: 10.7270/Q2BR8TQP |
More data for this Ligand-Target Pair | |