BDBM50009463 CHEMBL3234145
SMILES: C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCC[N+](C)(C)C)C(=O)N[C@@H](CO)C(N)=O
InChI Key: InChIKey=CMAVMDKQDSBJEX-NELKFLMZSA-O
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chromobox protein homolog 7 (Homo sapiens (Human)) | BDBM50009463 (CHEMBL3234145) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Victoria Curated by ChEMBL | Assay Description Displacement of FITC-labeled H3K27me3 from CBX7 (unknown origin) after 15 mins by fluorescence polarization assay | J Med Chem 57: 2874-83 (2014) Article DOI: 10.1021/jm401487x BindingDB Entry DOI: 10.7270/Q2571DJ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromobox protein homolog 7 (Homo sapiens (Human)) | BDBM50009463 (CHEMBL3234145) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Victoria Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged human CBX7 (8 to 62) expressed in Escherichia coli BL21 using FITC-peptide-3 as competitive binding probe ... | ACS Med Chem Lett 7: 139-44 (2016) BindingDB Entry DOI: 10.7270/Q2222WNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromobox protein homolog 8 (Homo sapiens (Human)) | BDBM50009463 (CHEMBL3234145) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.23E+4 | n/a | n/a | n/a | n/a | n/a |
University of Victoria Curated by ChEMBL | Assay Description Binding affinity to CBX8 (unknown origin) by isothermal titration calorimetry assay | J Med Chem 57: 2874-83 (2014) Article DOI: 10.1021/jm401487x BindingDB Entry DOI: 10.7270/Q2571DJ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromobox protein homolog 7 (Homo sapiens (Human)) | BDBM50009463 (CHEMBL3234145) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.77E+3 | n/a | n/a | n/a | n/a | n/a |
University of Victoria Curated by ChEMBL | Assay Description Binding affinity to CBX7 (unknown origin) by isothermal titration calorimetry assay | J Med Chem 57: 2874-83 (2014) Article DOI: 10.1021/jm401487x BindingDB Entry DOI: 10.7270/Q2571DJ3 | |||||||||||
More data for this Ligand-Target Pair |