BDBM50009486 CHEMBL3234168

SMILES: CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](CCCC[N+](C)(C)C)C(=O)NCCN

InChI Key: InChIKey=NKNGUMRMENYDJR-OXCFDMGDSA-O

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50009486   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chromobox protein homolog 7 (CBX7) (Homo sapiens (Human))	BDBM50009486 (CHEMBL3234168) Show SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](CCCC[N+](C)(C)C)C(=O)NCCN |r| Show InChI InChI=1S/C31H53N7O5/c1-21(2)19-26(31(43)36-25(29(41)33-17-16-32)15-11-12-18-38(5,6)7)37-28(40)22(3)34-30(42)27(35-23(4)39)20-24-13-9-8-10-14-24/h8-10,13-14,21-22,25-27H,11-12,15-20,32H2,1-7H3,(H4-,33,34,35,36,37,39,40,41,42,43)/p+1/t22-,25-,26-,27-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Victoria Curated by ChEMBL					Assay Description Displacement of FITC-labeled H3K27me3 from CBX7 (unknown origin) after 15 mins by fluorescence polarization assay				J Med Chem 57: 2874-83 (2014) Article DOI: 10.1021/jm401487x BindingDB Entry DOI: 10.7270/Q2571DJ3
					More data for this Ligand-Target Pair