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BDBM50009487 CHEMBL3234169

SMILES: CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](CCCC[N+](C)(C)C)C(=O)NCCNC(=O)OC(C)(C)C

InChI Key: InChIKey=JVQGXWATDWRJRC-ABYARXGNSA-O

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50009487   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chromobox protein homolog 7 (CBX7)


(Homo sapiens (Human))		BDBM50009487
PNG
(CHEMBL3234169)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](CCCC[N+](C)(C)C)C(=O)NCCNC(=O)OC(C)(C)C |r|
Show InChI InChI=1S/C36H61N7O7/c1-24(2)22-29(42-31(45)25(3)39-33(47)30(40-26(4)44)23-27-16-12-11-13-17-27)34(48)41-28(18-14-15-21-43(8,9)10)32(46)37-19-20-38-35(49)50-36(5,6)7/h11-13,16-17,24-25,28-30H,14-15,18-23H2,1-10H3,(H5-,37,38,39,40,41,42,44,45,46,47,48,49)/p+1/t25-,28-,29-,30-/m0/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.05E+5n/an/an/an/an/an/a



University of Victoria

Curated by ChEMBL


Assay Description
Displacement of FITC-labeled H3K27me3 from CBX7 (unknown origin) after 15 mins by fluorescence polarization assay

J Med Chem 57: 2874-83 (2014)


Article DOI: 10.1021/jm401487x
BindingDB Entry DOI: 10.7270/Q2571DJ3
More data for this
Ligand-Target Pair