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SMILES: OC(=O)Cc1nn(Cc2nc3cccnc3s2)c(=O)c2ccccc12

InChI Key: InChIKey=ALGOKUNLOGYVHW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50009769   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aldo-keto reductase family 1 member B1


(Homo sapiens (Human))		BDBM50009769
PNG
((4-Oxo-3-thiazolo[5,4-b]pyridin-2-ylmethyl-3,4-dih...)
Show SMILES OC(=O)Cc1nn(Cc2nc3cccnc3s2)c(=O)c2ccccc12
Show InChI InChI=1S/C17H12N4O3S/c22-15(23)8-13-10-4-1-2-5-11(10)17(24)21(20-13)9-14-19-12-6-3-7-18-16(12)25-14/h1-7H,8-9H2,(H,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 10n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta.

J Med Chem 34: 108-22 (1991)


BindingDB Entry DOI: 10.7270/Q2513X6H
More data for this
Ligand-Target Pair