null
SMILES: [Br-].NC(=[NH2+])SCc1ccc(CS(=O)(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1
InChI Key: InChIKey=LEVRBPUPQLAKHA-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Plasma kallikrein (Homo sapiens (Human)) | BDBM50009926 (CHEMBL3250026) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 3.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
TBA Curated by ChEMBL | Assay Description Competitive inhibition of 2 X 10'-7 M human plasma kallikrein using Z-Lys-nitrophenyl ester as substrate incubated up to 1 hr at pH 6 | J Med Chem 21: 456-9 (1978) BindingDB Entry DOI: 10.7270/Q2736SFF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Bos taurus (Bovine)) | BDBM50009926 (CHEMBL3250026) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 9.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
TBA Curated by ChEMBL | Assay Description Competitive inhibition of 16 X 10'-7 M bovine thrombin using Z-Lys-nitrophenyl ester as substrate incubated up to 1 hr at pH 6 | J Med Chem 21: 456-9 (1978) BindingDB Entry DOI: 10.7270/Q2736SFF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50009926 (CHEMBL3250026) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 1.20E+6 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
TBA Curated by ChEMBL | Assay Description Competitive inhibition of 4.8 X 10'-7 M human plasmin using Z-Lys-nitrophenyl ester as substrate incubated up to 1 hr at pH 6 | J Med Chem 21: 456-9 (1978) BindingDB Entry DOI: 10.7270/Q2736SFF | |||||||||||
More data for this Ligand-Target Pair |