BDBM50010337 CHEMBL3263582
SMILES: OC(=O)c1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1Cc1ccccc1
InChI Key: InChIKey=SSSCOJOXPDDHOO-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50010337 (CHEMBL3263582) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.820 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins ... | Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50010337 (CHEMBL3263582) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by ABPP-SILAC-based LC-MS/MS analysis | Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50010337 (CHEMBL3263582) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by gel-based competitive ABPP assay | Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50010337 (CHEMBL3263582) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant mouse ABHD6 expressed in HEK293T using 2-arachidonoylglycerol preincubated for 30 mins followed by substrate addition measu... | Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR | |||||||||||
More data for this Ligand-Target Pair |