BDBM50010660 CHEMBL3264749

SMILES: CC1(C)CC(CC(C)(C)N1)NC(=O)c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=NAIJPKJHTAKSJV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50010660   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50010660 (CHEMBL3264749) Show SMILES CC1(C)CC(CC(C)(C)N1)NC(=O)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C22H28N2O2/c1-21(2)14-17(15-22(3,4)24-21)23-20(25)16-10-12-19(13-11-16)26-18-8-6-5-7-9-18/h5-13,17,24H,14-15H2,1-4H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Constellation Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of wild type EZH2 (unknown origin)				ACS Med Chem Lett 5: 378-83 (2014) Article DOI: 10.1021/ml400494b BindingDB Entry DOI: 10.7270/Q2BP04BR
					More data for this Ligand-Target Pair