BDBM50010696 (R)-2-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL276326
SMILES: CN1CCc2cc(Br)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31
InChI Key: InChIKey=SETZXJXEHHDPBP-CYBMUJFWSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50010696 ((R)-2-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 17.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Debrecen Curated by ChEMBL | Assay Description Displacement of [3H]raclopride from dopamine D2 receptor in rat striatal membrane | Bioorg Med Chem 16: 4563-8 (2008) Article DOI: 10.1016/j.bmc.2008.02.038 BindingDB Entry DOI: 10.7270/Q24J0DW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50010696 ((R)-2-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Binding affinity at rat striatal Dopamine receptor D2 using [3H]- piperone radioligand | J Med Chem 33: 1800-5 (1990) BindingDB Entry DOI: 10.7270/Q2K35SMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50010696 ((R)-2-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenz...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 106 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Binding affinity at rat striatal Dopamine receptor D1 using [3H]- SCH-23390 radioligand | J Med Chem 33: 1800-5 (1990) BindingDB Entry DOI: 10.7270/Q2K35SMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50010696 ((R)-2-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 728 | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Compound was evaluated for the ability to displace [3H]-spiperone at Dopamine receptor D2 in porcine anterior pituitary gland as low affinity state | J Med Chem 32: 1198-201 (1989) BindingDB Entry DOI: 10.7270/Q2Q23Z7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50010696 ((R)-2-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Compound was evaluated for the ability to displace [3H]-spiperone at Dopamine receptor D2 in porcine anterior pituitary gland as high affinity state | J Med Chem 32: 1198-201 (1989) BindingDB Entry DOI: 10.7270/Q2Q23Z7P | |||||||||||
More data for this Ligand-Target Pair |