BDBM50010717 8-Chloro-3-methyl-5-o-tolyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL444321

SMILES: CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1C

InChI Key: InChIKey=IUSYOTYODLWHQQ-MRXNPFEDSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50010717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50010717 (8-Chloro-3-methyl-5-o-tolyl-2,3,4,5-tetrahydro-1H-...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1C Show InChI InChI=1S/C18H20ClNO/c1-12-5-3-4-6-14(12)16-11-20(2)8-7-13-9-17(19)18(21)10-15(13)16/h3-6,9-10,16,21H,7-8,11H2,1-2H3/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Binding affinity to displace [3H]- SCH 23390 against Dopamine receptor D1				J Med Chem 33: 2197-204 (1990) BindingDB Entry DOI: 10.7270/Q2TD9XZB
					More data for this Ligand-Target Pair