BDBM50010748 CHEMBL540291::N-(3,5-Dimethyl-adamantan-1-yl)-N'-o-tolyl-guanidine; hydrochloride

SMILES: Cc1ccccc1N=C(N)NC12CC3CC(C)(CC(C)(C3)C1)C2

InChI Key: InChIKey=NSOJADJSIOHGHB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50010748   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50010748 (CHEMBL540291 | N-(3,5-Dimethyl-adamantan-1-yl)-N'-...) Show SMILES Cc1ccccc1N=C(N)NC12CC3CC(C)(CC(C)(C3)C1)C2 |w:7.7,TLB:14:15:21:13.12.20,20:18:22:13.12.14,20:13:22:18.21.17,THB:19:18:22:13.12.14,16:15:21:13.12.20,14:13:21:15.22.17| Show InChI InChI=1S/C20H29N3/c1-14-6-4-5-7-16(14)22-17(21)23-20-10-15-8-18(2,12-20)11-19(3,9-15)13-20/h4-7,15H,8-13H2,1-3H3,(H3,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Oregon Curated by ChEMBL					Assay Description In vitro inhibitory activity against [3H]DTG binding to Sigma opioid receptor in guinea pig brain membrane homogenates				J Med Chem 33: 2421-9 (1990) BindingDB Entry DOI: 10.7270/Q25Q4WQ3
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