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BDBM50011163 4-(6-Amino-purin-9-yl)-but-2-yn-1-ol::CHEMBL46348

SMILES: Nc1ncnc2n(CC#CCO)cnc12

InChI Key: InChIKey=SRIQEESUOZNCLN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011163   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosylhomocysteinase


(Homo sapiens (Human))
BDBM50011163
PNG
(4-(6-Amino-purin-9-yl)-but-2-yn-1-ol | CHEMBL46348)
Show SMILES Nc1ncnc2n(CC#CCO)cnc12
Show InChI InChI=1S/C9H9N5O/c10-8-7-9(12-5-11-8)14(6-13-7)3-1-2-4-15/h5-6,15H,3-4H2,(H2,10,11,12)
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MMDB

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PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
Evaluated for the 50% inhibition of bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase


J Med Chem 31: 1729-38 (1988)


BindingDB Entry DOI: 10.7270/Q2HM5920
More data for this
Ligand-Target Pair