BDBM50011193 5-tert-Butyl-3-[2-(1-carboxy-3-phenyl-propylamino)-propionyl]-2,3-dihydro-[1,3,4]thiadiazole-2-carboxylic acid(FPL 63674)::CHEMBL342372::Utibaprilat

SMILES: C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1N=C(S[C@H]1C(O)=O)C(C)(C)C

InChI Key: InChIKey=APWZQGVRPRWXQK-NOLJZWGESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011193   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin-converting enzyme (Rattus norvegicus)	BDBM50011193 (5-tert-Butyl-3-[2-(1-carboxy-3-phenyl-propylamino)...) Show SMILES C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1N=C(S[C@H]1C(O)=O)C(C)(C)C |c:19| Show InChI InChI=1S/C20H27N3O5S/c1-12(21-14(17(25)26)11-10-13-8-6-5-7-9-13)15(24)23-16(18(27)28)29-19(22-23)20(2,3)4/h5-9,12,14,16,21H,10-11H2,1-4H3,(H,25,26)(H,27,28)/t12-,14-,16-/m0/s1	KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.510	n/a	n/a	n/a	n/a	n/a	n/a
Research and Development Laboratories Curated by ChEMBL					Assay Description Compound was tested for inhibitory activity against angiotensin I converting enzyme				J Med Chem 34: 439-47 (1991) BindingDB Entry DOI: 10.7270/Q28P5ZGR
					More data for this Ligand-Target Pair