BDBM50011437 2-(4-Amino-phenyl)-chromen-4-one::2-(4-aminophenyl)-4H-chromen-4-one::CHEMBL352730

SMILES: Nc1ccc(cc1)-c1cc(=O)c2ccccc2o1

InChI Key: InChIKey=ULEQUBHNFINDKW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011437   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50011437 (2-(4-Amino-phenyl)-chromen-4-one | 2-(4-aminopheny...) Show SMILES Nc1ccc(cc1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C15H11NO2/c16-11-7-5-10(6-8-11)15-9-13(17)12-3-1-2-4-14(12)18-15/h1-9H,16H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of p56 lck				J Nat Prod 55: 1529-1560 (1992) Article DOI: 10.1021/np50089a001 BindingDB Entry DOI: 10.7270/Q2J966CC
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50011437 (2-(4-Amino-phenyl)-chromen-4-one | 2-(4-aminopheny...) Show SMILES Nc1ccc(cc1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C15H11NO2/c16-11-7-5-10(6-8-11)15-9-13(17)12-3-1-2-4-14(12)18-15/h1-9H,16H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to inhibit protein-tyrosine kinase activity of p56lck (isolated from bovine thymus) in vitro.				J Med Chem 34: 798-806 (1991) BindingDB Entry DOI: 10.7270/Q2CF9P3J
					More data for this Ligand-Target Pair