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SMILES: Cc1cc(cnc1N)-c1cccc(N)c1

InChI Key: InChIKey=IFAIBDQJJDLOMM-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011548   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase kinase kinase kinase 4


(Homo sapiens (Human))		BDBM50011548
PNG
(CHEMBL3262567)
Show SMILES Cc1cc(cnc1N)-c1cccc(N)c1
Show InChI InChI=1S/C12H13N3/c1-8-5-10(7-15-12(8)14)9-3-2-4-11(13)6-9/h2-7H,13H2,1H3,(H2,14,15)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/a 6.80E+4n/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Binding affinity to N-terminal His-tagged C-terminal Avi-tagged MAP4K4 (unknown origin) expressed in baculovirus expression system by surface plasmon...

J Med Chem 57: 3484-93 (2014)


Article DOI: 10.1021/jm500155b
BindingDB Entry DOI: 10.7270/Q2M046ZR
More data for this
Ligand-Target Pair