BDBM50011572 CHEMBL3262871

SMILES: CC(NC(=O)c1cccc(c1)-c1ccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1)c1ccccc1

InChI Key: InChIKey=SZAPQHXYXAURBX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011572   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50011572 (CHEMBL3262871) Show SMILES CC(NC(=O)c1cccc(c1)-c1ccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1)c1ccccc1 Show InChI InChI=1S/C29H23ClF3N3O2/c1-18(19-6-3-2-4-7-19)34-27(37)22-9-5-8-21(16-22)20-10-12-23(13-11-20)35-28(38)36-24-14-15-26(30)25(17-24)29(31,32)33/h2-18H,1H3,(H,34,37)(H2,35,36,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking Union Medical College& Chinese Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of C-Raf (unknown origin) after 1 hr by ADP-Glo assay				Eur J Med Chem 77: 351-60 (2014) Article DOI: 10.1016/j.ejmech.2014.03.020 BindingDB Entry DOI: 10.7270/Q2G73G8W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50011572 (CHEMBL3262871) Show SMILES CC(NC(=O)c1cccc(c1)-c1ccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1)c1ccccc1 Show InChI InChI=1S/C29H23ClF3N3O2/c1-18(19-6-3-2-4-7-19)34-27(37)22-9-5-8-21(16-22)20-10-12-23(13-11-20)35-28(38)36-24-14-15-26(30)25(17-24)29(31,32)33/h2-18H,1H3,(H,34,37)(H2,35,36,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking Union Medical College& Chinese Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of B-Raf (unknown origin) after 1 hr by ADP-Glo assay				Eur J Med Chem 77: 351-60 (2014) Article DOI: 10.1016/j.ejmech.2014.03.020 BindingDB Entry DOI: 10.7270/Q2G73G8W
					More data for this Ligand-Target Pair