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SMILES: Cc1nnc2CN=C(c3cc(sc3-n12)C#CCn1c2CCCCc2c2ccccc12)c1ccccc1Cl

InChI Key: InChIKey=AJAUSFIERKQXFW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011605   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Homo sapiens (Human))		BDBM50011605
PNG
(4-(2-Chloro-phenyl)-9-methyl-2-[3-(1,2,3,4-tetrahy...)
Show SMILES Cc1nnc2CN=C(c3cc(sc3-n12)C#CCn1c2CCCCc2c2ccccc12)c1ccccc1Cl |c:6|
Show InChI InChI=1S/C30H24ClN5S/c1-19-33-34-28-18-32-29(23-12-2-5-13-25(23)31)24-17-20(37-30(24)36(19)28)9-8-16-35-26-14-6-3-10-21(26)22-11-4-7-15-27(22)35/h2-3,5-6,10,12-14,17H,4,7,11,15-16,18H2,1H3
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n/an/a 7n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
PAF-antagonist activity determined in dog platelets by PAF-binding assay

J Med Chem 34: 1209-21 (1991)


BindingDB Entry DOI: 10.7270/Q23X85M1
More data for this
Ligand-Target Pair