null
SMILES: C[C@@H]1N=C(c2ccccc2F)c2cc(ccc2-n2c(C)nnc12)C#CCN1C(=O)CCc2ccccc12
InChI Key: InChIKey=VTXDWOOLDDTASH-IBGZPJMESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet-activating factor receptor (Homo sapiens (Human)) | BDBM50011612 (1-{3-[6-(2-Fluoro-phenyl)-1,4-dimethyl-4H-2,3,5,10...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description PAF-antagonist activity determined in dog platelets by PAF-binding assay | J Med Chem 34: 1209-21 (1991) BindingDB Entry DOI: 10.7270/Q23X85M1 | |||||||||||
More data for this Ligand-Target Pair |