BindingDB logo
myBDB logout

null

SMILES: Cc1nnc2CN=C(c3ccccc3Cl)c3cc(ccc3-n12)C#CCN1C(=O)c2cccc3cccc(C1=O)c23

InChI Key: InChIKey=PAETVDHVOHYOBY-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011619   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Homo sapiens (Human))		BDBM50011619
PNG
(2-{3-[6-(2-Chloro-phenyl)-1-methyl-4H-2,3,5,10b-te...)
Show SMILES Cc1nnc2CN=C(c3ccccc3Cl)c3cc(ccc3-n12)C#CCN1C(=O)c2cccc3cccc(C1=O)c23 |t:6|
Show InChI InChI=1S/C32H20ClN5O2/c1-19-35-36-28-18-34-30(22-10-2-3-13-26(22)33)25-17-20(14-15-27(25)38(19)28)7-6-16-37-31(39)23-11-4-8-21-9-5-12-24(29(21)23)32(37)40/h2-5,8-15,17H,16,18H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 15n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
PAF-antagonist activity determined in dog platelets by PAF-binding assay

J Med Chem 34: 1209-21 (1991)


BindingDB Entry DOI: 10.7270/Q23X85M1
More data for this
Ligand-Target Pair