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SMILES: Cc1nnc2CN=C(c3cc(sc3-n12)C#CCn1c2ccccc2c(=O)c2ccccc2c1=O)c1ccccc1Cl

InChI Key: InChIKey=YNOKRTBTNJUUOA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011625   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Homo sapiens (Human))		BDBM50011625
PNG
(5-{3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8...)
Show SMILES Cc1nnc2CN=C(c3cc(sc3-n12)C#CCn1c2ccccc2c(=O)c2ccccc2c1=O)c1ccccc1Cl |c:6|
Show InChI InChI=1S/C32H20ClN5O2S/c1-19-35-36-28-18-34-29(23-12-4-6-14-26(23)33)25-17-20(41-32(25)38(19)28)9-8-16-37-27-15-7-5-13-24(27)30(39)21-10-2-3-11-22(21)31(37)40/h2-7,10-15,17H,16,18H2,1H3
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n/an/a 6n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
PAF-antagonist activity determined in dog platelets by PAF-binding assay

J Med Chem 34: 1209-21 (1991)


BindingDB Entry DOI: 10.7270/Q23X85M1
More data for this
Ligand-Target Pair