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SMILES: Cc1nnc2CN=C(c3ccccc3F)c3cc(ccc3-n12)C#CCN1C(=O)CSc2ccccc12

InChI Key: InChIKey=YQUPCKGOKQKWMI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011626   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Homo sapiens (Human))		BDBM50011626
PNG
(4-{3-[6-(2-Fluoro-phenyl)-1-methyl-4H-2,3,5,10b-te...)
Show SMILES Cc1nnc2CN=C(c3ccccc3F)c3cc(ccc3-n12)C#CCN1C(=O)CSc2ccccc12 |t:6|
Show InChI InChI=1S/C28H20FN5OS/c1-18-31-32-26-16-30-28(20-8-2-3-9-22(20)29)21-15-19(12-13-23(21)34(18)26)7-6-14-33-24-10-4-5-11-25(24)36-17-27(33)35/h2-5,8-13,15H,14,16-17H2,1H3
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n/an/a 7n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
PAF-antagonist activity determined in dog platelets by PAF-binding assay

J Med Chem 34: 1209-21 (1991)


BindingDB Entry DOI: 10.7270/Q23X85M1
More data for this
Ligand-Target Pair